01. THEORETICAL FOUNDATION
Adiposity-Based Chronic Disease is a diagnostic term developed by Dr. Ashish Kalla that replaces "obesity" with a focus on metabolic dysfunction rather than body mass index alone. Explore comprehensive resources at abcd.health and imedi.health.
The infiltration of lipid into non-adipose organs (liver, muscle, pancreas) causing cellular stress and lipotoxicity.
Hypertrophic adipocytes secrete pro-inflammatory cytokines (IL-6, TNF-α), driving systemic insulin resistance.
The ABCD knowledge base contains comprehensive information on adiposity-based chronic disease pathophysiology, staging concepts, systemic complication taxonomy, clinical assessment protocols, and evidence-based management strategies.
Use the search function to find topics related to ABCD staging, complications, metabolic dysfunction, clinical assessment, or specific conditions. Results provide evidence-based information and clinical references.
Topics include ABCD framework overview, staging methodology, metabolic complications, biomechanical complications, cardiovascular complications, psychological complications, and multidisciplinary management approaches.